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References

The following were used as reference on adult growth hormone deficiency and human growth hormone:

  1. Burke. Growth hormone and aging. Endocrine 1998:8:103 – 108.
  2. Ceda GP, Dall”Aglio E, Magnacavallo A et al. the insulin –like growth factor Axis and plasma lipid levels in the elderly. J Clin Endocrinol Metab 1998; 83 : 499-502
  3. Bjorntorp P. Neuroendocrine aging. J Intern Med 1995; 238:401-404.
  4. Jorgensen JOL.., Pederson SA, Thuesen L et al. Beneficial effects of growth hormone treatment in growth hormone deficient articles. Lancet 1989; i : 1221-1225
  5. de Boer H, Block G, van der Veen EA. Clinical aspects of growth hormone deficiency in adults .Endocr Rev 1995; 16: 63-86
  6. de Boer H, Blok GH, Van Lingen A, Teule GJJ, Lips P, van der Veen EA. The consequences of childhood onset growth hormone deficiency for adult bone mass. J Bone Miner Res 1994; 9: 1319-1326
  7. Attanasio AF, Lamberts SWJ, Matranga AMC et al. under growth hormone [GH] and deficient patients demonstrate heterogenicity between childhood onset and other onset before and during human growth hormone treatment. J Clinc Endocrinol Metab 1997; 82: 82-88
  8. Finkelstein JW, Boyar RM, Roffwarg HP, Kream J, Hellman L, age-related changes in the 24-hour spontaneous secretion of growth hormone. J Clinc Endocrinol Metab 1972; 35: 665 -- 7 0.
  9. Clemmons DR, Van Wyk JJ. factors controlling bled concentration of somatomedin C. Clin Endocrinol Metab 1984: 1 3: 113 -- 4 3.
  10. Rudman D, growth hormone, body composition Kamath and aging. J Am Geriatr Soc 1985; 33: 800-7.
  11. Rudman D, Kutner MH, Rogers CM, Lubin MF, Fleming GA, Bain RP. Impaired growth hormone secretion in the adult population: relation to age in adiposity. J Clin Invest 1981; 67: 1361-9
  12. Florini JR, Prinz PN, Vitiello MV, Hintz RI. Somatomedin C. levels in healthy young and old men: relationship to peak and 24-hour integrated levels of growth hormone. J Gerontol 1985: 4 0: 2-7.
  13. Rudman D, Kutner MH, Rogers CM, Lubin MF, Fleming GA, Bain RP. Impaired growth hormone secretion in the adult population: relation to age in adiposity. J Clin Invest 1981; 67: 1361-9
  14. Florini JR, Prinz PN, Vitiello MV, Hintz RI. Somatomedin C. levels in healthy young and old men: relationship to peak and 24-hour integrated levels of growth hormone. J Gerontol 1985: 4 0: 2-7.
  15. Rudman D, growth hormone, body composition Kamath and aging. J Am Geriatr Soc 1985; 33: 800-7.
  16. van an Buul-Offers S, Van den Brande JL. The growth of different organs of normal and dwarfed small mice, before and during GH therapy. Acta Endocrinol 1981; 96:46-58
  17. Parra A, Argote RM, Garcia G, Cervantes C, Alatorre S, Perez-Pasten E, body composition in hypopituitary dwarfs before and during growth hormone therapy. Metabolism 1979; 28: 851 -- 7.
  18. van der Werff ten Bosch JJ, Bot A. effects of human pituitary growth hormone on body composition. Neth J med 1987: 30:220-7
  19. Crist DM, Peake GT. Mackinnon LT, Sibbitt WL Jr, Kraner JC. Exogenous growth hormone treatment alters body composition and increases natural killer cell activity in women with impaired endogenous growth hormone secretion. Metabolism 1987; 36: 1115 -- 7.
  20. Jergensen JOL, Pedersen SA, Thuesen L, et al. beneficial effects of growth treatment in growth hormone deficient adults. Lancet 1989; 1: 1221 -- 5.
  21. Crist DM, Peake GT, Egan PA, Waters DL. Body composition response to exogenous growth hormone during training in highly conditioned adults. J Appl Physiol 1988; 65: 579-84.
  22. Salomon F, Cuneo RC, Hesp R, Sonksen PH. The effect of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl Med 1989; 321:1797-803.
  23. Ahmad, et.al, Effects of GH Replacement on 24-h ambulatory blood pressure and its circadian rhythm in adult GH deficiency, Clinical Endocrinology, May 2002, Vol 56, Number 56: 431-437
  24. Braverman, E., Human Growth Hormone Replacement Therapy, Poster Presentation for the American Academy of Anti-Aging Medicine, Dec 2001
  25. Cook, D., Shouldn’t adults with GH deficiency be offered HG replacement therapy?, Annals of Internal Medicine, May 2002, Vol 137: 197-201
  26. Gotherstrom, G, et al., A prospective study of 5 years of GH replacement therapy…, Journal of Clinical Endocrine and Meta, Oct 2001, 86 (10): 4657-65
  27. Gibney, J., et al. The effects of 10 years of recombinant human growth hormone, in adults GH deficient patients, The Journal of Clin Endocrine and Metab, August 1999, Vol 84, Number
  28. Hader, K, et al. Growth hormone release to clonidine and the clinical response to levodopa in parkinsonism, JAGA, Letters to the Editors, Sept 2002, 50 (9): 1609-10
  29. Murray Ge, et al. Low dose GH replacement improves the adverse lipid profile associated with the adult GH deficiency syndrome, Clinical Endocrinology, 2002, Volume 56: 525-32
  30. Oomen, P, et al., Reduced capillary permeability and capillary density in the skin of GH deficient adults: Improvement after 12 months GH replacement, Clinical Endocrinology, 2002, Vol 56: 519-524
  31. Sonntag, W. The effects of growth hormone and IGF-1 efficiency on cerebravascular and brain aging, 2000, Vol 197: 575-585
  32. Rosenfeld, R. G., et al: Diagnostic controversy: The diagnosis of childhood growth hormone deficiency revisited, Journal of Clinical Endocrinology and Metabolism, 1995, 80, 1532-1540.
  33. Kemp, S: Growth Hormone Deficiency Overview, Jan 2002, e-Medicine
  34. Dash RJ, Muralidharan R, Talwar V., Growth Hormone Therapy, Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
  35. Ogilvy-Stuart et al. BMJ 1992; 304: 1601-1605
  36. Ritzen et al. Horm. Res. 1993; 39: 99-101
  37. Sklar CA, Mertens AC, Mitby P, Occhiogrosso G, Qin J, Heller G, Yasui Y, Robison LL.Department of Pediatrics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA., J Clin Endocrinol Metab, Risk of disease recurrence and second neoplasm’s in survivors of childhood cancer treated with growth hormone: a report from the Childhood Cancer Survivor Study. 2002 Jul;87(7):3136-41

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